Pulmonary Mycoses in Indonesia: Current Situations and Future Challenges
DOI:
https://doi.org/10.36497/jri.v39i3.69Keywords:
pulmonary mycoses, epidemiology changes, Pulmonary Mycoses CenterAbstract
Cases of pulmonary mycosis or pulmonary fungal diseases continues to increase in frequency along with the expanding population with impaired immune systems, including patients with pre-existing pulmonary diseases. Changing profile of underlying diseases might cause altering diseases profile as well. In previous decades, Pneumocystis pneumonia was the most common pulmonary mycosis in HIV-infected patients. As the increasing number of TB cases, pulmonary malignancy, chronic obstructive pulmonary disease (COPD) and certain chronic diseases, other pulmonary mycoses also increase such as chronic pulmonary aspergillosis, cryptococcosis, histoplasmosis, and other filamentous fungal infection. Furthermore, the airborne fungal particles of Aspergillus and other fungi could seriously worsen asthma or allergic respiratory diseases. In low- and middle-income countries, including Indonesia, lack of diagnostic facilities may lead to inadequate treatment. It will contribute to poor clinical outcomes with high mortality rates. The awareness among clinicians and other health workers of this epidemiology changes is the important step in early diagnosis and better managemenet of pulmonary mycosis in the future. (J Respir Indo. 2019; 39(3): 210-4)Downloads
References
Cuenca-Estrella M, Bernal-Martinez L, Buitrago MJ, Castelli MV, Zaragoza O, Rodriguez-Tudela JL. Update on the epidemiology and diagnosis of invasive fungal infection. Int J Antimicrob. 2008;32:143-7.
Limper AH. The changing spectrum of fungal infections in pulmonary and critical care practice: clinical approach to diagnosis. Proc Am Thorac Soc. 2010;7:163–8.
Rozaliyani A, Jusuf A, Handayani D, Burhan E, Soepandi PZ, Nawas MA, dkk. Mikosis Paru: pedoman nasional untuk diagnosis dan penatalaksanaan di Indonesia. Perhimpunan Dokter Paru Indonesia. 2nd ed. Jakarta, 2017.p.11-2.
Denning DW. Introduction. In: Pasqualotto AC, editor. Aspergillosis: from diagnosis to prevention. 1st ed. London: Springer; 2010.p.3-5.
Kauffman CA, Nicolasora NP. Epidemiology of invasive pulmonary aspergillosis. In: Pasqualotto AC, editor. Aspergillosis: from diagnosis to prevention. 1st ed. London: Springer; 2010.p.329-44.
Denning DW, Pleuvry A, Cole DC. Global burden of chronic pulmonary aspergillosis as a sequel to pulmonary tuberculosis. Bulletin WHO.2011;89:864-72.
He H, Ding L, Li F, Zhan Q. Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study. Crit Care. 2011;15:1-12.
Wahyuningsih R, Rozaliyani A, Wahjuani W, Wibawanto A, Fajar Y, Andarini D. Chronic cavitary pulmonary aspergillosis in previous TB cases with recurrent hemoptysis. 6th Advance Against Aspergillosis Meeting (AAA, oral presentation), Istanbul, Turkey, 2012.
Tutar N, Metan G, Koç AN, Yilmaz I, Bozkurt I, Demir R. Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Multidisciplin Resp Med. 2013; 8:1-7.
Bulpa P, Dive A, Sibille Y. Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Eur Respir J. 2007;30(4):782-800.
Ader F, Nseir R, Leroy LB, Tillie‐Leblond I, Marquette CH, Durocher A. Invasive pulmonary aspergillosis in chronic obstructive pulmonary disease: an emerging fungal pathogen. Clin Microbiol Infect. 2005;11: 427-9.
Ohmagari N, Raad IM, Hachem R, Kontoyiannis DP. Invasive aspergillosis in patients with solid tumors. Cancer. 2004;101:2300–2.
Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G. Immunological aspects of cancer chemotherapy. Nat Rev Immunol. 2008;8:59-73.
Denning DW, Pleuvry A, Cole DC. Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. Med Mycol. 2013;51:361–70.
Mihardja LK, Delima A, Soetiarto, Kristanto AY. Penyakit tidak menular. In: FA, Kepala Badan, editor. Pokok-pokok hasil Riskesdas 2013. Jakarta: Kemenkes RI;2013:117-21.
Patterson K, Strek ME. Allergic bronchopulmonary aspergillosis. Proc Am Thorac Soc 2010;7:237-44.
Groll AH, Shah PM, Mentzel C. Trends in the postmortem epidemiology of invasive fungal infections at a university hospital. J Infect. 1996;33:23–32.
Alangden GJ. Nosocomial Fungal Infections: Epidemiology, Infection Control, and Prevention. Infect Dis Clin N Am. 2011;25:201–25.
Suleyman G, Alangden GJ. Nosocomial Fungal Infections Epidemiology, Infection Control, and Prevention. Infect Dis Clin N Am. 2016;30:1023–52.
Rozaliyani A. Karakteristik klinis, radiologis dan laboratoris Pneumonia Pneumo-cystis pada pasien AIDS dengan gejala pneumonia di beberapa rumah sakit di Jakarta. [Thesis]. Jakarta: Universitas Indonesia; 2008.
Rozaliyani A. Aspergilosis paru invasif pada pasien ICU: model skoring diagnosis, karakteristik klinis dan laboratoris, serta profil kepekaan Aspergillus terhadap obat antijamur. [Dissertation]. Jakarta: Universitas Indonesia; 2015.
Faik A. Profil kolonisasi jamur pada pasien asma persisten, hubungannya terhadap asma, status kontrol asma dan fungsi paru di Rumah Sakit Umum Pusat Persahabatan. [Thesis]. Jakarta: Universitas Indonesia; 2017.
Stopiati F. Profil kolonisasi jamur pada pasien bekas tuberkulosis paru multi drug resistance di RSUP Persahabatan. [Thesis]. Jakarta: Universitas Indonesia; 2016.
De Pauw B, Walsh TJ, Donnelly JP, Stevens DA, Edwards JE, Calandra T, et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis. 2008;46:1813–21.
Limper AH, Knox KS, Sarosi GA, Ampel NM, Bennett JE, Catanzaro A, et al. An official American Thoracic Society statement: Treatment of fungal infections in adult pulmonary and critical care patients. Am J Respir Crit Care Med. 2011;183:96–128.
Downloads
Additional Files
Published
Issue
Section
License
- The authors own the copyright of published articles. Nevertheless, Jurnal Respirologi Indonesia has the first-to-publish license for the publication material.
- Jurnal Respirologi Indonesia has the right to archive, change the format and republish published articles by presenting the authors’ names.
- Articles are published electronically for open access and online for educational, research, and archiving purposes. Jurnal Respirologi Indonesia is not responsible for any copyright issues that might emerge from using any article except for the previous three purposes.
