Email the author The Comparison Between Risk Factors of Invasive Candidiasis and 1,3-β-D-Glucan in Septic Pneumonia
Abstract
Method: this cross-sectional study was conducted in 40 patients with septic pneumonia in ICU who had the risk factors of IC (multifocal colonization, broad-spectrum antibiotics, long term use of corticosteroids, and lymphocyte status) at Saiful Anwar Malang General Hospital.
Results: There were 40 patients with risk factors of IC had positive BDG, but only 1 patient (2,5%) had candidemia and 14 patients (35%) had Candida sp from sputum culture. Comparison of BDG levels between group which used broad-spectrum antibiotics and those that did not wassignificant (P=0.020). Rank Spearman linear regression of the lymphocyte <1.200 cells/mm3 on BDG levels had a positive correlation (r=2.7%, P=0.880) while linear regression of the lymphocyte <1.200 cells/mm3 had a negative correlation (r=-32.1%, P=0.428).
Conclusion: Septic pneumonia patients with Candida risk factors in the ICU might have superinfection with IC. The use of broad-spectrum antibiotics affected BDG levels more significant than other risk factors.
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DOI: https://doi.org/10.36497/jri.v40i4.132
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